HCSGD entry for TRRAP
1. General information
| Official gene symbol | TRRAP |
|---|---|
| Entrez ID | 8295 |
| Gene full name | transformation/transcription domain-associated protein |
| Other gene symbols | PAF350/400 PAF400 STAF40 TR-AP Tra1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000125 | PCAF complex | NAS | cellular_component |
| GO:0003712 | Transcription cofactor activity | IDA | molecular_function |
| GO:0003713 | Transcription coactivator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0007093 | Mitotic cell cycle checkpoint | IEA | biological_process |
| GO:0016573 | Histone acetylation | NAS | biological_process |
| GO:0016578 | Histone deubiquitination | IDA | biological_process |
| GO:0016773 | Phosphotransferase activity, alcohol group as acceptor | IEA | molecular_function |
| GO:0030914 | STAGA complex | IDA | cellular_component |
| GO:0033276 | Transcription factor TFTC complex | IDA | cellular_component |
| GO:0035267 | NuA4 histone acetyltransferase complex | IDA | cellular_component |
| GO:0043967 | Histone H4 acetylation | IDA | biological_process |
| GO:0043968 | Histone H2A acetylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6476277459 | 0.0322078720 | 0.9999902473 | 0.3376902828 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0891321598 |
| GSE13712_SHEAR | Up | 0.0103162191 |
| GSE13712_STATIC | Down | -0.1574860472 |
| GSE19018 | Down | -0.0578329802 |
| GSE19899_A1 | Down | -0.3367963137 |
| GSE19899_A2 | Down | -0.6358112932 |
| PubMed_21979375_A1 | Down | -0.6978000264 |
| PubMed_21979375_A2 | Down | -0.3496501437 |
| GSE35957 | Down | -0.5065539727 |
| GSE36640 | Down | -0.7633411774 |
| GSE54402 | Up | 0.2749260338 |
| GSE9593 | Down | -0.3287376232 |
| GSE43922 | Down | -0.0801798686 |
| GSE24585 | Down | -0.2183523715 |
| GSE37065 | Down | -0.1454578335 |
| GSE28863_A1 | Up | 1.2836825973 |
| GSE28863_A2 | Up | 1.3124569189 |
| GSE28863_A3 | Down | -0.1144020769 |
| GSE28863_A4 | Down | -0.3002843945 |
| GSE48662 | Down | -0.3108422949 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017022 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021348 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028429 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036039 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036320 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-760 | MIMAT0004957 | MIRT036716 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041264 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-330-3p | MIMAT0000751 | MIRT043836 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044338 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045381 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047272 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-31-5p | MIMAT0000089 | MIRT049886 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050404 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050991 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051634 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051861 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052563 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
