HCSGD entry for CAPZA2


1. General information

Official gene symbolCAPZA2
Entrez ID830
Gene full namecapping protein (actin filament) muscle Z-line, alpha 2
Other gene symbolsCAPPA2 CAPZ
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006461Protein complex assemblyTASbiological_process
GO:0006928Cellular component movementTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008290F-actin capping protein complexIEAcellular_component
GO:0015629Actin cytoskeletonTAScellular_component
GO:0016020MembraneIEAcellular_component
GO:0030036Actin cytoskeleton organizationIEAbiological_process
GO:0030863Cortical cytoskeletonIEAcellular_component
GO:0045087Innate immune responseTASbiological_process
GO:0051693Actin filament cappingIEAbiological_process
GO:0071203WASH complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59410505300.34654551120.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1144270940
GSE13712_SHEARUp0.0471301553
GSE13712_STATICDown-0.0947203818
GSE19018Down-0.0271770942
GSE19899_A1Up0.1493598137
GSE19899_A2Up0.0151651862
PubMed_21979375_A1Up0.4372264137
PubMed_21979375_A2Up0.1609765185
GSE35957Up0.1375893084
GSE36640Up0.0653404987
GSE54402Up0.0564952478
GSE9593Down-0.1746114563
GSE43922Down-0.0212871048
GSE24585Up0.0874548186
GSE37065Up0.2002610717
GSE28863_A1Down-0.1716856784
GSE28863_A2Up0.2960383119
GSE28863_A3Down-0.3564063453
GSE28863_A4Down-0.1701113380
GSE48662Down-0.4673026711

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-103a-3pMIMAT0000101MIRT027222SequencingFunctional MTI (Weak)20371350
hsa-miR-16-5pMIMAT0000069MIRT031933SequencingFunctional MTI (Weak)20371350
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.