HCSGD entry for NME5
1. General information
| Official gene symbol | NME5 |
|---|---|
| Entrez ID | 8382 |
| Gene full name | NME/NM23 family member 5 |
| Other gene symbols | NM23-H5 NM23H5 RSPH23 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003351 | Epithelial cilium movement | IEA | biological_process |
| GO:0004550 | Nucleoside diphosphate kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0006183 | GTP biosynthetic process | IEA | biological_process |
| GO:0006228 | UTP biosynthetic process | IEA | biological_process |
| GO:0006241 | CTP biosynthetic process | IEA | biological_process |
| GO:0007283 | Spermatogenesis | TAS | biological_process |
| GO:0007286 | Spermatid development | ISS | biological_process |
| GO:0009116 | Nucleoside metabolic process | TAS | biological_process |
| GO:0021591 | Ventricular system development | IEA | biological_process |
| GO:0036126 | Sperm flagellum | IEA | cellular_component |
| GO:0042384 | Cilium assembly | IEA | biological_process |
| GO:1902176 | Negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1773632005 | 0.3013980054 | 0.8264646257 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1860128691 |
| GSE13712_SHEAR | Down | -1.4431337152 |
| GSE13712_STATIC | Up | 0.0146510881 |
| GSE19018 | Down | -0.1419531297 |
| GSE19899_A1 | Down | -0.1248633400 |
| GSE19899_A2 | Down | -0.1106474608 |
| PubMed_21979375_A1 | Up | 0.0690077874 |
| PubMed_21979375_A2 | Up | 0.3326606819 |
| GSE35957 | Up | 0.1299983209 |
| GSE36640 | Up | 1.5141045908 |
| GSE54402 | Down | -0.1658413571 |
| GSE9593 | Up | 0.6749330729 |
| GSE43922 | Down | -0.0365638677 |
| GSE24585 | Down | -0.0080690002 |
| GSE37065 | Down | -0.0378651093 |
| GSE28863_A1 | Down | -0.1424626084 |
| GSE28863_A2 | Down | -0.0798814816 |
| GSE28863_A3 | Up | 0.0552083761 |
| GSE28863_A4 | Down | -0.0590963847 |
| GSE48662 | Up | 0.4299060402 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019446 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029961 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
