HCSGD entry for USP44

1. General information

Official gene symbolUSP44
Entrez ID84101
Gene full nameubiquitin specific peptidase 44
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004221Ubiquitin thiolesterase activityIEA IMPmolecular_function
GO:0004843Ubiquitin-specific protease activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0007067MitosisIEAbiological_process
GO:0008234Cysteine-type peptidase activityIEAmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016579Protein deubiquitinationIDAbiological_process
GO:0043161Proteasome-mediated ubiquitin-dependent protein catabolic processISSbiological_process
GO:0051322AnaphaseIMPbiological_process
GO:0060564Negative regulation of mitotic anaphase-promoting complex activityIMPbiological_process
GO:0090231Regulation of spindle checkpointIMPbiological_process
GO:0090266Regulation of mitotic cell cycle spindle assembly checkpointISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73902721020.00171698640.99999024730.0794414035

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1656333998
GSE13712_SHEARUp0.3867705242
GSE13712_STATICUp0.7515960276
GSE19018Down-0.1458330895
GSE19899_A1Down-2.2599629465
GSE19899_A2Down-3.7950047499
PubMed_21979375_A1Down-2.4583141176
PubMed_21979375_A2Down-4.2225703504
GSE35957Up0.0021309265
GSE36640Down-1.6951107709
GSE54402Down-1.8848277691
GSE9593Down-0.0087890660
GSE43922Down-2.0177789887
GSE24585Up0.1579593349
GSE37065Down-0.0796812179
GSE28863_A1Up0.0884925953
GSE28863_A2Up0.5893626562
GSE28863_A3Up0.1038348231
GSE28863_A4Down-0.0812707177
GSE48662Down-0.0232694462

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017223MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.