HCSGD entry for SYDE2
1. General information
| Official gene symbol | SYDE2 |
|---|---|
| Entrez ID | 84144 |
| Gene full name | synapse defective 1, Rho GTPase, homolog 2 (C. elegans) |
| Other gene symbols | RP11-33E12.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005100 | Rho GTPase activator activity | ISS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0032862 | Activation of Rho GTPase activity | ISS | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8494090612 | 0.0139711371 | 0.9999902473 | 0.2324936829 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0714652759 |
| GSE13712_SHEAR | Down | -0.1636243142 |
| GSE13712_STATIC | Up | 0.3153665188 |
| GSE19018 | Down | -0.1918690606 |
| GSE19899_A1 | Down | -0.3652810719 |
| GSE19899_A2 | Down | -0.3912085244 |
| PubMed_21979375_A1 | Up | 0.3224239623 |
| PubMed_21979375_A2 | Down | -0.3201680836 |
| GSE35957 | Up | 0.3061396820 |
| GSE36640 | Up | 0.0146123623 |
| GSE54402 | Down | -0.5368488334 |
| GSE9593 | Up | 0.1767464933 |
| GSE43922 | Down | -0.4543918820 |
| GSE24585 | Up | 0.0031845898 |
| GSE37065 | Down | -0.1162220559 |
| GSE28863_A1 | Down | -0.6940524250 |
| GSE28863_A2 | Up | 0.3706566696 |
| GSE28863_A3 | Down | -1.0676391262 |
| GSE28863_A4 | Down | -0.4079366726 |
| GSE48662 | Up | 0.1609359396 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-378a-5p | MIMAT0000731 | MIRT043965 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046326 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
