HCSGD entry for LCOR
1. General information
| Official gene symbol | LCOR |
|---|---|
| Entrez ID | 84458 |
| Gene full name | ligand dependent nuclear receptor corepressor |
| Other gene symbols | MLR2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0008134 | Transcription factor binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0552006421 | 0.3675957296 | 0.5117883222 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7465849413 |
| GSE13712_SHEAR | Up | 0.6082641126 |
| GSE13712_STATIC | Up | 0.5681937888 |
| GSE19018 | Down | -0.0754796465 |
| GSE19899_A1 | Up | 0.4900336773 |
| GSE19899_A2 | Up | 0.2776438675 |
| PubMed_21979375_A1 | Up | 0.5228722446 |
| PubMed_21979375_A2 | Up | 0.3457006322 |
| GSE35957 | Down | -0.1476572492 |
| GSE36640 | Up | 0.1838489951 |
| GSE54402 | Up | 0.5074756687 |
| GSE9593 | Down | -0.5702670324 |
| GSE43922 | Up | 0.0367485389 |
| GSE24585 | Down | -0.0049037224 |
| GSE37065 | Up | 0.2471187153 |
| GSE28863_A1 | Up | 0.4792348950 |
| GSE28863_A2 | Up | 0.2778089182 |
| GSE28863_A3 | Down | -0.6745590597 |
| GSE28863_A4 | Down | -0.0307934218 |
| GSE48662 | Down | -0.5089911133 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT007027 | Luciferase reporter assay | Functional MTI | 21565892 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT016678 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018627 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027215 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027388 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037058 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041427 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046212 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050889 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
