HCSGD entry for KISS1R
1. General information
| Official gene symbol | KISS1R |
|---|---|
| Entrez ID | 84634 |
| Gene full name | KISS1 receptor |
| Other gene symbols | AXOR12 GPR54 HH8 HOT7T175 KISS-1R |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000186 | Activation of MAPKK activity | IEA | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | NAS | biological_process |
| GO:0007218 | Neuropeptide signaling pathway | IDA | biological_process |
| GO:0007268 | Synaptic transmission | IDA | biological_process |
| GO:0007610 | Behavior | NAS | biological_process |
| GO:0008188 | Neuropeptide receptor activity | IDA | molecular_function |
| GO:0008285 | Negative regulation of cell proliferation | IEA | biological_process |
| GO:0009986 | Cell surface | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IDA IEA | cellular_component |
| GO:0019722 | Calcium-mediated signaling | IEA | biological_process |
| GO:0042923 | Neuropeptide binding | IEA | molecular_function |
| GO:0046887 | Positive regulation of hormone secretion | IEA | biological_process |
| GO:0050482 | Arachidonic acid secretion | IEA | biological_process |
| GO:0050806 | Positive regulation of synaptic transmission | IEA | biological_process |
| GO:0051496 | Positive regulation of stress fiber assembly | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2320192508 | 0.8313835607 | 0.9156997153 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7122664557 |
| GSE13712_SHEAR | Up | 0.1294569752 |
| GSE13712_STATIC | Down | -0.0053681798 |
| GSE19018 | Up | 0.1039266374 |
| GSE19899_A1 | Up | 0.2372530553 |
| GSE19899_A2 | Up | 0.0629226562 |
| PubMed_21979375_A1 | Up | 0.0603693942 |
| PubMed_21979375_A2 | Down | -0.1781176878 |
| GSE35957 | Up | 0.1231500365 |
| GSE36640 | Up | 0.0784564287 |
| GSE54402 | Up | 0.2030266950 |
| GSE9593 | Up | 0.1849347994 |
| GSE43922 | Up | 0.1105737167 |
| GSE24585 | Up | 0.2750024192 |
| GSE37065 | Up | 0.0254510079 |
| GSE28863_A1 | Up | 0.0018989983 |
| GSE28863_A2 | Down | -0.0635654300 |
| GSE28863_A3 | Up | 0.3737350644 |
| GSE28863_A4 | Up | 0.1585992315 |
| GSE48662 | Down | -0.0432294445 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23949429 | Interestingly, the polycomb repressive complex -2 (PCRC2) target genes Kiss1r, Nav2 and Hsf4 were hypermethylated with age |
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