HCSGD entry for KLHL22
1. General information
| Official gene symbol | KLHL22 |
|---|---|
| Entrez ID | 84861 |
| Gene full name | kelch-like family member 22 |
| Other gene symbols | KELCHL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000070 | Mitotic sister chromatid segregation | IMP | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005827 | Polar microtubule | IDA | cellular_component |
| GO:0006513 | Protein monoubiquitination | IDA | biological_process |
| GO:0007094 | Mitotic spindle assembly checkpoint | IMP | biological_process |
| GO:0031463 | Cul3-RING ubiquitin ligase complex | IDA | cellular_component |
| GO:0051301 | Cell division | IMP | biological_process |
| GO:0072686 | Mitotic spindle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7512406861 | 0.3131773565 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1249281821 |
| GSE13712_SHEAR | Down | -0.5524356405 |
| GSE13712_STATIC | Down | -0.1574244942 |
| GSE19018 | Up | 0.0712140612 |
| GSE19899_A1 | Down | -0.1247189053 |
| GSE19899_A2 | Down | -0.0877482257 |
| PubMed_21979375_A1 | Down | -0.1400754299 |
| PubMed_21979375_A2 | Down | -0.1924285240 |
| GSE35957 | Down | -0.0596367001 |
| GSE36640 | Down | -0.1594352824 |
| GSE54402 | Down | -0.0333588453 |
| GSE9593 | Down | -0.0264911596 |
| GSE43922 | Down | -0.0593566706 |
| GSE24585 | Up | 0.2560465637 |
| GSE37065 | Down | -0.0700171040 |
| GSE28863_A1 | Down | -0.0487067527 |
| GSE28863_A2 | Down | -0.3308476230 |
| GSE28863_A3 | Up | 0.0643511560 |
| GSE28863_A4 | Up | 0.3184823943 |
| GSE48662 | Up | 0.5773910330 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT039836 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041412 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
