HCSGD entry for RSPO3
1. General information
| Official gene symbol | RSPO3 |
|---|---|
| Entrez ID | 84870 |
| Gene full name | R-spondin 3 |
| Other gene symbols | CRISTIN1 PWTSR THSD2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005109 | Frizzled binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0060070 | Canonical Wnt signaling pathway | IEA | biological_process |
| GO:0060670 | Branching involved in labyrinthine layer morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0254776034 | 0.0987087991 | 0.3746346369 | 0.6011370430 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5291026883 |
| GSE13712_SHEAR | Down | -1.8728693110 |
| GSE13712_STATIC | Down | -1.3942148115 |
| GSE19018 | Down | -0.2614655864 |
| GSE19899_A1 | Up | 0.2643145934 |
| GSE19899_A2 | Up | 1.1208968915 |
| PubMed_21979375_A1 | Up | 3.3763722186 |
| PubMed_21979375_A2 | Up | 0.9247557621 |
| GSE35957 | Down | -1.5428730686 |
| GSE36640 | Down | -0.0285684032 |
| GSE54402 | Down | -0.6230389536 |
| GSE9593 | Down | -0.0022426005 |
| GSE43922 | Up | 0.0199818511 |
| GSE24585 | Up | 0.1015241360 |
| GSE37065 | Up | 0.6615740680 |
| GSE28863_A1 | Down | -0.0823798228 |
| GSE28863_A2 | Up | 0.3025122566 |
| GSE28863_A3 | Up | 0.2995263425 |
| GSE28863_A4 | Down | -0.0836287783 |
| GSE48662 | Up | 0.6868094419 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017040 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
