HCSGD entry for PIK3R3

1. General information

Official gene symbolPIK3R3
Entrez ID8503
Gene full namephosphoinositide-3-kinase, regulatory subunit 3 (gamma)
Other gene symbolsp55 p55-GAMMA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0005942Phosphatidylinositol 3-kinase complexIEAcellular_component
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006661Phosphatidylinositol biosynthetic processTASbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:00163031-phosphatidylinositol-3-kinase activityTASmolecular_function
GO:0016310PhosphorylationTASbiological_process
GO:0035014Phosphatidylinositol 3-kinase regulator activityIEAmolecular_function
GO:0036092Phosphatidylinositol-3-phosphate biosynthetic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046854Phosphatidylinositol phosphorylationTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.20896363740.61326236090.88087530431.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2414986387
GSE13712_SHEARUp0.0241888831
GSE13712_STATICDown-0.0053029607
GSE19018Down-0.3312885558
GSE19899_A1Up0.0579749572
GSE19899_A2Down-0.0508203915
PubMed_21979375_A1Down-0.2402418501
PubMed_21979375_A2Up0.4559411024
GSE35957Up0.0749579131
GSE36640Up0.6542132729
GSE54402Down-0.1801457178
GSE9593Up0.3793997930
GSE43922Down-0.0433145578
GSE24585Up0.1756698287
GSE37065Up0.8815639221
GSE28863_A1Down-0.4585040315
GSE28863_A2Up0.1470329375
GSE28863_A3Down-0.0264488229
GSE28863_A4Down-0.0133383735
GSE48662Down-0.1608764273

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

SF1126DB05210 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-18a-3pMIMAT0002891MIRT040803CLASHFunctional MTI (Weak)23622248
hsa-miR-346MIMAT0000773MIRT042712CLASHFunctional MTI (Weak)23622248
hsa-miR-331-3pMIMAT0000760MIRT043293CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.