HCSGD entry for PTCH2
1. General information
| Official gene symbol | PTCH2 |
|---|---|
| Entrez ID | 8643 |
| Gene full name | patched 2 |
| Other gene symbols | PTC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005119 | Smoothened binding | IPI | molecular_function |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008158 | Hedgehog receptor activity | TAS | molecular_function |
| GO:0008544 | Epidermis development | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0042633 | Hair cycle | IEA | biological_process |
| GO:0045879 | Negative regulation of smoothened signaling pathway | TAS | biological_process |
| GO:0097108 | Hedgehog family protein binding | IPI TAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7026505300 | 0.6752037119 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1149124113 |
| GSE13712_SHEAR | Down | -0.1177709214 |
| GSE13712_STATIC | Down | -0.0473436844 |
| GSE19018 | Up | 0.1580721834 |
| GSE19899_A1 | Up | 0.0346092820 |
| GSE19899_A2 | Down | -0.0696636096 |
| PubMed_21979375_A1 | Down | -0.0656553585 |
| PubMed_21979375_A2 | Down | -0.0218899155 |
| GSE35957 | Up | 0.2102866827 |
| GSE36640 | Down | -0.0649452924 |
| GSE54402 | Down | -0.0539107646 |
| GSE9593 | Down | -0.0078650398 |
| GSE43922 | Down | -0.1395277892 |
| GSE24585 | Up | 0.0668569876 |
| GSE37065 | Down | -0.2062244082 |
| GSE28863_A1 | Up | 0.1167912922 |
| GSE28863_A2 | Up | 0.1790595188 |
| GSE28863_A3 | Up | 0.2127092964 |
| GSE28863_A4 | Up | 0.1161545793 |
| GSE48662 | Up | 0.1132230445 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
