HCSGD entry for IL18R1
1. General information
| Official gene symbol | IL18R1 |
|---|---|
| Entrez ID | 8809 |
| Gene full name | interleukin 18 receptor 1 |
| Other gene symbols | CD218a CDw218a IL-1Rrp IL18RA IL1RRP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0004908 | Interleukin-1 receptor activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030101 | Natural killer cell activation | IEA | biological_process |
| GO:0032729 | Positive regulation of interferon-gamma production | IEA | biological_process |
| GO:0042008 | Interleukin-18 receptor activity | IEA | molecular_function |
| GO:0042346 | Positive regulation of NF-kappaB import into nucleus | IEA | biological_process |
| GO:0045063 | T-helper 1 cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2206922533 | 0.3813153680 | 0.9019175229 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0866790425 |
| GSE13712_SHEAR | Down | -1.1774739090 |
| GSE13712_STATIC | Up | 0.4425816878 |
| GSE19018 | Down | -0.1930711841 |
| GSE19899_A1 | Up | 0.1066135927 |
| GSE19899_A2 | Up | 0.5269349159 |
| PubMed_21979375_A1 | Up | 0.4942939985 |
| PubMed_21979375_A2 | Up | 0.3869873290 |
| GSE35957 | Up | 0.0813171652 |
| GSE36640 | Down | -0.8569491029 |
| GSE54402 | Up | 0.0676334585 |
| GSE9593 | Down | -0.6553656824 |
| GSE43922 | Up | 0.0774374600 |
| GSE24585 | Up | 0.1107885663 |
| GSE37065 | Up | 0.0254605896 |
| GSE28863_A1 | Up | 0.6486944269 |
| GSE28863_A2 | Down | -0.0018380229 |
| GSE28863_A3 | Up | 0.2231244691 |
| GSE28863_A4 | Down | -0.0900785320 |
| GSE48662 | Up | 0.0018976625 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023090 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
