HCSGD entry for WISP2


1. General information

Official gene symbolWISP2
Entrez ID8839
Gene full nameWNT1 inducible signaling pathway protein 2
Other gene symbolsCCN5 CT58 CTGF-L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001558Regulation of cell growthIEAbiological_process
GO:0005520Insulin-like growth factor bindingIEAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00232595270.89454595570.12884936971.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0278349469
GSE13712_SHEARUp0.0698738381
GSE13712_STATICUp0.0317499970
GSE19018Up0.0937733495
GSE19899_A1Up0.0238346893
GSE19899_A2Up0.1436147963
PubMed_21979375_A1Up0.1270639671
PubMed_21979375_A2Down-0.1697642780
GSE35957Down-0.2084142227
GSE36640Up0.0378252847
GSE54402Down-0.0438002808
GSE9593Up2.9017577105
GSE43922Up0.1360981893
GSE24585Up0.0674095384
GSE37065Up0.3656666503
GSE28863_A1Up1.7464750144
GSE28863_A2Up1.8751044579
GSE28863_A3Up0.6365133642
GSE28863_A4Up0.0366615660
GSE48662Up0.7782606317

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-449aMIMAT0001541MIRT006502Luciferase reporter assayFunctional MTI19351815
hsa-miR-124-3pMIMAT0000422MIRT022148MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-449aMIMAT0001541NAhsa-miR-449a19351815
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.