HCSGD entry for PGLYRP1
1. General information
| Official gene symbol | PGLYRP1 |
|---|---|
| Entrez ID | 8993 |
| Gene full name | peptidoglycan recognition protein 1 |
| Other gene symbols | PGLYRP PGRP PGRP-S PGRPS TAG7 TNFSF3L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002221 | Pattern recognition receptor signaling pathway | IDA | biological_process |
| GO:0005576 | Extracellular region | NAS | cellular_component |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0007165 | Signal transduction | IDA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008745 | N-acetylmuramoyl-L-alanine amidase activity | IEA | molecular_function |
| GO:0009253 | Peptidoglycan catabolic process | IEA | biological_process |
| GO:0016019 | Peptidoglycan receptor activity | IDA | molecular_function |
| GO:0016045 | Detection of bacterium | IDA | biological_process |
| GO:0032689 | Negative regulation of interferon-gamma production | IEA | biological_process |
| GO:0032827 | Negative regulation of natural killer cell differentiation involved in immune response | IEA | biological_process |
| GO:0042834 | Peptidoglycan binding | IDA | molecular_function |
| GO:0044117 | Growth of symbiont in host | IEA | biological_process |
| GO:0045087 | Innate immune response | NAS | biological_process |
| GO:0050830 | Defense response to Gram-positive bacterium | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5625700467 | 0.8309229247 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0275929868 |
| GSE13712_SHEAR | Down | -0.0651729603 |
| GSE13712_STATIC | Up | 0.0078844021 |
| GSE19018 | Up | 0.1482180814 |
| GSE19899_A1 | Down | -0.0130457099 |
| GSE19899_A2 | Up | 0.1659180765 |
| PubMed_21979375_A1 | Down | -0.1884390334 |
| PubMed_21979375_A2 | Down | -0.0388122200 |
| GSE35957 | Up | 0.2358036163 |
| GSE36640 | Up | 0.0216411924 |
| GSE54402 | Down | -0.0523210936 |
| GSE9593 | Up | 0.2138934597 |
| GSE43922 | Up | 0.0690453730 |
| GSE24585 | Up | 0.1277138654 |
| GSE37065 | Down | -0.1724082493 |
| GSE28863_A1 | Up | 0.0067554614 |
| GSE28863_A2 | Down | -0.1218496309 |
| GSE28863_A3 | Up | 0.1516856399 |
| GSE28863_A4 | Up | 0.1463924984 |
| GSE48662 | Down | -0.1246375138 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018270 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051104 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
