HCSGD entry for CDKL2
1. General information
| Official gene symbol | CDKL2 |
|---|---|
| Entrez ID | 8999 |
| Gene full name | cyclin-dependent kinase-like 2 (CDC2-related kinase) |
| Other gene symbols | KKIAMRE P56 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA TAS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0004693 | Cyclin-dependent protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007548 | Sex differentiation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9067347213 | 0.6090823677 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0167457568 |
| GSE13712_SHEAR | Down | -0.0369422494 |
| GSE13712_STATIC | Down | -0.0624942813 |
| GSE19018 | Down | -0.0064008599 |
| GSE19899_A1 | Up | 0.0125953843 |
| GSE19899_A2 | Down | -0.0112959970 |
| PubMed_21979375_A1 | Down | -0.0928567303 |
| PubMed_21979375_A2 | Up | 0.0012115735 |
| GSE35957 | Up | 0.0679200911 |
| GSE36640 | Up | 0.0798080317 |
| GSE54402 | Down | -0.0631427102 |
| GSE9593 | Up | 0.1563785305 |
| GSE43922 | Down | -0.3740062703 |
| GSE24585 | Down | -0.0368331638 |
| GSE37065 | Down | -0.0605501627 |
| GSE28863_A1 | Down | -0.0803408552 |
| GSE28863_A2 | Up | 0.1787304482 |
| GSE28863_A3 | Up | 0.1727913537 |
| GSE28863_A4 | Down | -0.1181678984 |
| GSE48662 | Up | 0.0742381226 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028804 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
