HCSGD entry for UBA3
1. General information
| Official gene symbol | UBA3 |
|---|---|
| Entrez ID | 9039 |
| Gene full name | ubiquitin-like modifier activating enzyme 3 |
| Other gene symbols | UBE1C hUBA3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0006508 | Proteolysis | TAS | biological_process |
| GO:0007113 | Endomitotic cell cycle | IEA | biological_process |
| GO:0008641 | Small protein activating enzyme activity | IEA | molecular_function |
| GO:0016881 | Acid-amino acid ligase activity | IEA | molecular_function |
| GO:0045116 | Protein neddylation | IEA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0051726 | Regulation of cell cycle | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8977395958 | 0.2626382242 | 0.9999902473 | 0.9841829015 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1055949971 |
| GSE13712_SHEAR | Down | -0.1099097557 |
| GSE13712_STATIC | Up | 0.0163825087 |
| GSE19018 | Up | 0.2177859408 |
| GSE19899_A1 | Up | 0.2091735027 |
| GSE19899_A2 | Up | 0.1506734627 |
| PubMed_21979375_A1 | Up | 0.1355531253 |
| PubMed_21979375_A2 | Up | 0.0924135839 |
| GSE35957 | Down | -0.1625016317 |
| GSE36640 | Down | -0.0342825776 |
| GSE54402 | Down | -0.0915139685 |
| GSE9593 | Down | -0.0770959576 |
| GSE43922 | Down | -0.0478675797 |
| GSE24585 | Up | 0.1361550875 |
| GSE37065 | Up | 0.1307611682 |
| GSE28863_A1 | Down | -0.1504714225 |
| GSE28863_A2 | Down | -0.0293805665 |
| GSE28863_A3 | Down | -0.5162736855 |
| GSE28863_A4 | Down | -0.2351408198 |
| GSE48662 | Down | -0.4874916341 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020498 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032210 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
