HCSGD entry for LDB2
1. General information
| Official gene symbol | LDB2 |
|---|---|
| Entrez ID | 9079 |
| Gene full name | LIM domain binding 2 |
| Other gene symbols | CLIM1 LDB1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001942 | Hair follicle development | IEA | biological_process |
| GO:0003712 | Transcription cofactor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0010669 | Epithelial structure maintenance | IEA | biological_process |
| GO:0019899 | Enzyme binding | IEA | molecular_function |
| GO:0030274 | LIM domain binding | IEA ISS | molecular_function |
| GO:0035019 | Somatic stem cell maintenance | IEA | biological_process |
| GO:0044089 | Positive regulation of cellular component biogenesis | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9713383268 | 0.0017592721 | 0.9999902473 | 0.0801524221 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2084655409 |
| GSE13712_SHEAR | Down | -0.4156719144 |
| GSE13712_STATIC | Down | -0.2894593167 |
| GSE19018 | Up | 0.0554737604 |
| GSE19899_A1 | Down | -0.1319106239 |
| GSE19899_A2 | Down | -1.4995615048 |
| PubMed_21979375_A1 | Down | -1.1589254092 |
| PubMed_21979375_A2 | Down | -0.8849448497 |
| GSE35957 | Up | 0.2263785813 |
| GSE36640 | Down | -1.2931547588 |
| GSE54402 | Down | -0.6401694422 |
| GSE9593 | Up | 0.1086347947 |
| GSE43922 | Down | -1.4426367293 |
| GSE24585 | Up | 0.2800651262 |
| GSE37065 | Down | -0.3111538850 |
| GSE28863_A1 | Up | 0.5951235467 |
| GSE28863_A2 | Down | -0.9069070425 |
| GSE28863_A3 | Down | -1.0880399224 |
| GSE28863_A4 | Down | -0.0740765675 |
| GSE48662 | Down | -0.2861494133 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030241 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
