HCSGD entry for MTA1
1. General information
| Official gene symbol | MTA1 |
|---|---|
| Entrez ID | 9112 |
| Gene full name | metastasis associated 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001103 | RNA polymerase II repressing transcription factor binding | IPI | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016581 | NuRD complex | IEA | cellular_component |
| GO:0019899 | Enzyme binding | IEA | molecular_function |
| GO:0033363 | Secretory granule organization | IEA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8555409711 | 0.1181296607 | 0.9999902473 | 0.6601466667 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0583519659 |
| GSE13712_SHEAR | Down | -0.4151128158 |
| GSE13712_STATIC | Down | -0.2512224032 |
| GSE19018 | Up | 0.1429210838 |
| GSE19899_A1 | Down | -0.0826908631 |
| GSE19899_A2 | Up | 0.6866698292 |
| PubMed_21979375_A1 | Down | -0.5128749270 |
| PubMed_21979375_A2 | Down | -0.4721537073 |
| GSE35957 | Down | -0.0252756187 |
| GSE36640 | Down | -0.2533241260 |
| GSE54402 | Up | 0.0364144432 |
| GSE9593 | Down | -0.1238944755 |
| GSE43922 | Down | -0.0946192718 |
| GSE24585 | Down | -0.3476714441 |
| GSE37065 | Down | -0.3935191905 |
| GSE28863_A1 | Up | 0.1127723759 |
| GSE28863_A2 | Down | -0.0158884329 |
| GSE28863_A3 | Up | 0.0552857816 |
| GSE28863_A4 | Up | 0.0116900858 |
| GSE48662 | Up | 0.1858217716 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-661 | MIMAT0003324 | MIRT000033 | Luciferase reporter assay//Western blot | Functional MTI | 19584269 |
| hsa-miR-559 | MIMAT0003223 | MIRT004442 | Luciferase reporter assay//Western blot | Functional MTI | 19584269 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-661 | MIMAT0003324 | NA | hsa-miR-661 | {Western blot} | {overexpression} | 19584269 | |
| hsa-miR-559 | MIMAT0003223 | 1 | hsa-miR-559 | {Western blot} | {overexpression} | 19584269 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
