HCSGD entry for STK17A
1. General information
| Official gene symbol | STK17A |
|---|---|
| Entrez ID | 9263 |
| Gene full name | serine/threonine kinase 17a |
| Other gene symbols | DRAK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IDA | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IMP | biological_process |
| GO:2000271 | Positive regulation of fibroblast apoptotic process | IMP | biological_process |
| GO:2000377 | Regulation of reactive oxygen species metabolic process | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9126064055 | 0.0790776870 | 0.9999902473 | 0.5317081226 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0649862724 |
| GSE13712_SHEAR | Up | 0.0558627422 |
| GSE13712_STATIC | Down | -0.0288897210 |
| GSE19018 | Down | -0.8142759243 |
| GSE19899_A1 | Down | -0.1391183934 |
| GSE19899_A2 | Up | 0.1239445158 |
| PubMed_21979375_A1 | Down | -0.2328558827 |
| PubMed_21979375_A2 | Down | -0.4165261008 |
| GSE35957 | Down | -0.5047328171 |
| GSE36640 | Up | 0.2727068725 |
| GSE54402 | Down | -0.2716831948 |
| GSE9593 | Up | 0.1098294341 |
| GSE43922 | Down | -0.0423411471 |
| GSE24585 | Up | 0.2641370614 |
| GSE37065 | Up | 0.0445509342 |
| GSE28863_A1 | Down | -0.1254666014 |
| GSE28863_A2 | Up | 0.2952843956 |
| GSE28863_A3 | Down | -0.3406593105 |
| GSE28863_A4 | Down | -0.2600303088 |
| GSE48662 | Up | 0.0196377385 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
