HCSGD entry for GTF3C3
1. General information
| Official gene symbol | GTF3C3 |
|---|---|
| Entrez ID | 9330 |
| Gene full name | general transcription factor IIIC, polypeptide 3, 102kDa |
| Other gene symbols | TFIIIC102 TFIIICgamma TFiiiC2-102 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000127 | Transcription factor TFIIIC complex | IDA | cellular_component |
| GO:0003677 | DNA binding | IC | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IC | biological_process |
| GO:0006383 | Transcription from RNA polymerase III promoter | IC TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0042791 | 5S class rRNA transcription from RNA polymerase III type 1 promoter | IC | biological_process |
| GO:0042797 | TRNA transcription from RNA polymerase III promoter | IC | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8869350329 | 0.1650582501 | 0.9999902473 | 0.7861922186 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1569102885 |
| GSE13712_SHEAR | Up | 0.0941825805 |
| GSE13712_STATIC | Up | 0.0702351171 |
| GSE19018 | Down | -0.2237721191 |
| GSE19899_A1 | Down | -0.0324923508 |
| GSE19899_A2 | Down | -0.0602335178 |
| PubMed_21979375_A1 | Up | 0.1014330986 |
| PubMed_21979375_A2 | Down | -0.2547567634 |
| GSE35957 | Down | -0.1303762165 |
| GSE36640 | Down | -0.5611240523 |
| GSE54402 | Down | -0.1457164706 |
| GSE9593 | Down | -0.2605976131 |
| GSE43922 | Down | -0.0535227412 |
| GSE24585 | Up | 0.4312095303 |
| GSE37065 | Up | 0.1910502607 |
| GSE28863_A1 | Up | 0.0074105289 |
| GSE28863_A2 | Up | 0.2753600348 |
| GSE28863_A3 | Down | -0.8294867565 |
| GSE28863_A4 | Down | -0.2057456220 |
| GSE48662 | Down | -0.2228517165 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025544 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031970 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042107 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047868 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
