HCSGD entry for MED27


1. General information

Official gene symbolMED27
Entrez ID9442
Gene full namemediator complex subunit 27
Other gene symbolsCRAP34 CRSP34 CRSP8 TRAP37
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005667Transcription factor complexIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016592Mediator complexIEAcellular_component
GO:0019827Stem cell maintenanceIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58693987310.44190517080.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0239805898
GSE13712_SHEARDown-0.1980348479
GSE13712_STATICUp0.1972696053
GSE19018Up0.0307555042
GSE19899_A1Down-0.0439944766
GSE19899_A2Up0.4328088219
PubMed_21979375_A1Up0.4551977663
PubMed_21979375_A2Down-0.1622478589
GSE35957Down-0.5425607538
GSE36640Down-0.4176363493
GSE54402Up0.3081610636
GSE9593Down-0.0674793630
GSE43922Up0.0519026610
GSE24585Down-0.4273791091
GSE37065Down-0.1649293802
GSE28863_A1Up0.0453720759
GSE28863_A2Up0.1109236861
GSE28863_A3Up0.0626156552
GSE28863_A4Up0.1501605470
GSE48662Down-0.0801203622

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.