HCSGD entry for HOMER2
1. General information
| Official gene symbol | HOMER2 |
|---|---|
| Entrez ID | 9455 |
| Gene full name | homer homolog 2 (Drosophila) |
| Other gene symbols | ACPD CPD HOMER-2 VESL-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0007216 | G-protein coupled glutamate receptor signaling pathway | TAS | biological_process |
| GO:0008277 | Regulation of G-protein coupled receptor protein signaling pathway | IEA | biological_process |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030160 | GKAP/Homer scaffold activity | IEA | molecular_function |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0035256 | G-protein coupled glutamate receptor binding | IEA | molecular_function |
| GO:0035584 | Calcium-mediated signaling using intracellular calcium source | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
| GO:0048148 | Behavioral response to cocaine | IEA | biological_process |
| GO:0048875 | Chemical homeostasis within a tissue | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4279492155 | 0.2860452642 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1346222468 |
| GSE13712_SHEAR | Up | 0.0512176778 |
| GSE13712_STATIC | Down | -0.1190991353 |
| GSE19018 | Up | 0.1379795067 |
| GSE19899_A1 | Up | 0.0280792704 |
| GSE19899_A2 | Down | -0.0617703795 |
| PubMed_21979375_A1 | Up | 0.1113650776 |
| PubMed_21979375_A2 | Down | -0.0483978955 |
| GSE35957 | Down | -0.8127302538 |
| GSE36640 | Down | -0.1181802025 |
| GSE54402 | Up | 0.2551780981 |
| GSE9593 | Up | 0.0911235114 |
| GSE43922 | Up | 0.0391814670 |
| GSE24585 | Down | -0.6170915949 |
| GSE37065 | Down | -0.0396979097 |
| GSE28863_A1 | Up | 0.2518152399 |
| GSE28863_A2 | Down | -0.0385043681 |
| GSE28863_A3 | Up | 0.3316156269 |
| GSE28863_A4 | Down | -0.2373926480 |
| GSE48662 | Up | 0.1217137860 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019932 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-103a-2-5p | MIMAT0009196 | MIRT035764 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-125b-5p | MIMAT0000423 | NA | hsa-miR-125b | 18056640 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
