HCSGD entry for GTPBP1
1. General information
| Official gene symbol | GTPBP1 |
|---|---|
| Entrez ID | 9567 |
| Gene full name | GTP binding protein 1 |
| Other gene symbols | GP-1 GP1 HSPC018 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000177 | Cytoplasmic exosome (RNase complex) | IEA ISS | cellular_component |
| GO:0003924 | GTPase activity | IEA ISS | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | IEA ISS | cellular_component |
| GO:0006184 | GTP catabolic process | ISS | biological_process |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0061014 | Positive regulation of mRNA catabolic process | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1406641427 | 0.9565238935 | 0.7529561814 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0588725352 |
| GSE13712_SHEAR | Up | 0.0791017721 |
| GSE13712_STATIC | Up | 0.0732633940 |
| GSE19018 | Up | 0.0789575544 |
| GSE19899_A1 | Up | 0.1347005352 |
| GSE19899_A2 | Up | 0.2269928449 |
| PubMed_21979375_A1 | Up | 0.3456119836 |
| PubMed_21979375_A2 | Up | 0.4958210367 |
| GSE35957 | Down | -0.1892528097 |
| GSE36640 | Down | -0.0657594753 |
| GSE54402 | Up | 0.3146164360 |
| GSE9593 | Down | -0.0520873588 |
| GSE43922 | Up | 0.0737615464 |
| GSE24585 | Up | 0.1579403975 |
| GSE37065 | Up | 0.3660714925 |
| GSE28863_A1 | Up | 0.1510758073 |
| GSE28863_A2 | Down | -0.0867810548 |
| GSE28863_A3 | Down | -0.0729167495 |
| GSE28863_A4 | Up | 0.1590024614 |
| GSE48662 | Up | 0.3313592190 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027163 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031922 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038114 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041906 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043448 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048537 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
