HCSGD entry for SMG7
1. General information
| Official gene symbol | SMG7 |
|---|---|
| Entrez ID | 9887 |
| Gene full name | smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) |
| Other gene symbols | C1orf16 EST1C SGA56M |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0035303 | Regulation of dephosphorylation | TAS | biological_process |
| GO:0045111 | Intermediate filament cytoskeleton | IDA | cellular_component |
| GO:0051721 | Protein phosphatase 2A binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0485570153 | 0.9653543026 | 0.4864270209 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1002037672 |
| GSE13712_SHEAR | Up | 0.1976008299 |
| GSE13712_STATIC | Up | 0.0770445200 |
| GSE19018 | Up | 0.0273912329 |
| GSE19899_A1 | Up | 0.0992261056 |
| GSE19899_A2 | Up | 0.3484508048 |
| PubMed_21979375_A1 | Up | 1.0355877883 |
| PubMed_21979375_A2 | Up | 0.6498290122 |
| GSE35957 | Up | 0.0645309951 |
| GSE36640 | Down | -0.0391357769 |
| GSE54402 | Up | 0.4129303651 |
| GSE9593 | Up | 0.1107804079 |
| GSE43922 | Up | 0.5744695812 |
| GSE24585 | Down | -0.0757296716 |
| GSE37065 | Up | 0.1828117487 |
| GSE28863_A1 | Up | 0.2657025719 |
| GSE28863_A2 | Up | 0.4482003249 |
| GSE28863_A3 | Down | -0.3493572579 |
| GSE28863_A4 | Down | -0.2292313346 |
| GSE48662 | Up | 0.0167955754 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017118 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-935 | MIMAT0004978 | MIRT036693 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044347 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045344 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048833 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052266 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052606 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
