HCSGD entry for ACOT8
1. General information
| Official gene symbol | ACOT8 |
|---|---|
| Entrez ID | 10005 |
| Gene full name | acyl-CoA thioesterase 8 |
| Other gene symbols | HNAACTE PTE-1 PTE-2 PTE1 PTE2 hACTE-III hTE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005782 | Peroxisomal matrix | IDA IMP TAS | cellular_component |
| GO:0006637 | Acyl-CoA metabolic process | IDA IEA | biological_process |
| GO:0006699 | Bile acid biosynthetic process | TAS | biological_process |
| GO:0008206 | Bile acid metabolic process | TAS | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016290 | Palmitoyl-CoA hydrolase activity | IDA | molecular_function |
| GO:0016559 | Peroxisome fission | IDA | biological_process |
| GO:0033540 | Fatty acid beta-oxidation using acyl-CoA oxidase | TAS | biological_process |
| GO:0033559 | Unsaturated fatty acid metabolic process | TAS | biological_process |
| GO:0033882 | Choloyl-CoA hydrolase activity | IEA | molecular_function |
| GO:0036109 | Alpha-linolenic acid metabolic process | TAS | biological_process |
| GO:0043649 | Dicarboxylic acid catabolic process | IDA | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0047617 | Acyl-CoA hydrolase activity | IDA IEA | molecular_function |
| GO:0052815 | Medium-chain acyl-CoA hydrolase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1003565176 | 0.8935517572 | 0.6610320070 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0817459090 |
| GSE13712_SHEAR | Down | -0.2498990323 |
| GSE13712_STATIC | Down | -0.0569237143 |
| GSE19018 | Up | 0.0685106739 |
| GSE19899_A1 | Up | 0.1127118688 |
| GSE19899_A2 | Up | 1.2056603000 |
| PubMed_21979375_A1 | Up | 0.1206708611 |
| PubMed_21979375_A2 | Up | 0.9205156500 |
| GSE35957 | Down | -0.1230400037 |
| GSE36640 | Up | 0.7673657815 |
| GSE54402 | Up | 0.1799974713 |
| GSE9593 | Up | 0.1382356774 |
| GSE43922 | Up | 0.2299440823 |
| GSE24585 | Down | -0.0955348906 |
| GSE37065 | Down | -0.0718703266 |
| GSE28863_A1 | Up | 0.1157464048 |
| GSE28863_A2 | Down | -0.2796329539 |
| GSE28863_A3 | Down | -0.1464275746 |
| GSE28863_A4 | Down | -0.0782418257 |
| GSE48662 | Up | 0.3868961448 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016798 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031404 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
