HCSGD entry for SRA1
1. General information
| Official gene symbol | SRA1 |
|---|---|
| Entrez ID | 10011 |
| Gene full name | steroid receptor RNA activator 1 |
| Other gene symbols | SRA SRAP STRAA1 pp7684 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008283 | Cell proliferation | IDA | biological_process |
| GO:0010861 | Thyroid hormone receptor activator activity | IEA | molecular_function |
| GO:0030154 | Cell differentiation | IDA | biological_process |
| GO:0030374 | Ligand-dependent nuclear receptor transcription coactivator activity | IBA | molecular_function |
| GO:0030529 | Ribonucleoprotein complex | IPI | cellular_component |
| GO:0031252 | Cell leading edge | IEA | cellular_component |
| GO:0042981 | Regulation of apoptotic process | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:2000273 | Positive regulation of receptor activity | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0101884997 | 0.9310703887 | 0.2568692529 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.7270214433 |
| GSE13712_SHEAR | Down | -0.2836282691 |
| GSE13712_STATIC | Up | 0.0700256582 |
| GSE19018 | Up | 0.4440972790 |
| GSE19899_A1 | Up | 1.1314286001 |
| GSE19899_A2 | Up | 1.0400985296 |
| PubMed_21979375_A1 | Up | 1.5113323217 |
| PubMed_21979375_A2 | Up | 1.0647421133 |
| GSE35957 | Down | -0.3578165484 |
| GSE36640 | Up | 0.4253258174 |
| GSE54402 | Up | 0.6842694942 |
| GSE9593 | Up | 0.1017037626 |
| GSE43922 | Up | 0.4711567013 |
| GSE24585 | Down | -0.0230020589 |
| GSE37065 | Down | -0.2008763704 |
| GSE28863_A1 | Down | -0.0500033734 |
| GSE28863_A2 | Down | -0.1565113930 |
| GSE28863_A3 | Up | 0.0382405101 |
| GSE28863_A4 | Down | -0.1452124544 |
| GSE48662 | Down | -0.0398285450 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 10848625 | Interaction of the tau2 transcriptional activation domain of glucocorticoid receptor with a novel steroid receptor coactivator, Hic-5, which localizes to both focal adhesions and the nuclear matrix |
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