HCSGD entry for GNE
1. General information
| Official gene symbol | GNE |
|---|---|
| Entrez ID | 10020 |
| Gene full name | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| Other gene symbols | DMRV GLCNE IBM2 NM Uae1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006045 | N-acetylglucosamine biosynthetic process | IEA | biological_process |
| GO:0006047 | UDP-N-acetylglucosamine metabolic process | IEA | biological_process |
| GO:0006054 | N-acetylneuraminate metabolic process | TAS | biological_process |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0008761 | UDP-N-acetylglucosamine 2-epimerase activity | IEA | molecular_function |
| GO:0009103 | Lipopolysaccharide biosynthetic process | IEA | biological_process |
| GO:0009384 | N-acylmannosamine kinase activity | IEA | molecular_function |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0046380 | N-acetylneuraminate biosynthetic process | IEA | biological_process |
| GO:0046835 | Carbohydrate phosphorylation | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8289059648 | 0.0338385776 | 0.9999902473 | 0.3473277929 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3861453011 |
| GSE13712_SHEAR | Up | 0.2372716218 |
| GSE13712_STATIC | Down | -0.3247763460 |
| GSE19018 | Down | -0.0145630393 |
| GSE19899_A1 | Down | -0.5878822751 |
| GSE19899_A2 | Up | 0.1462736019 |
| PubMed_21979375_A1 | Up | 0.5504197662 |
| PubMed_21979375_A2 | Down | -0.9837540312 |
| GSE35957 | Down | -0.8296580892 |
| GSE36640 | Down | -0.4111587790 |
| GSE54402 | Down | -0.2388317896 |
| GSE9593 | Down | -0.0712104179 |
| GSE43922 | Down | -0.0023695404 |
| GSE24585 | Up | 0.3610194497 |
| GSE37065 | Up | 0.1421571962 |
| GSE28863_A1 | Down | -0.0780367119 |
| GSE28863_A2 | Down | -0.3873791115 |
| GSE28863_A3 | Down | -0.7647779877 |
| GSE28863_A4 | Up | 0.1085818119 |
| GSE48662 | Up | 0.5151071556 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030677 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
