HCSGD entry for PIGK
1. General information
| Official gene symbol | PIGK |
|---|---|
| Entrez ID | 10026 |
| Gene full name | phosphatidylinositol glycan anchor biosynthesis, class K |
| Other gene symbols | GPI8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003756 | Protein disulfide isomerase activity | TAS | molecular_function |
| GO:0003923 | GPI-anchor transamidase activity | IEA IMP TAS | molecular_function |
| GO:0004197 | Cysteine-type endopeptidase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0006501 | C-terminal protein lipidation | TAS | biological_process |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0016255 | Attachment of GPI anchor to protein | IEA TAS | biological_process |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | NAS | cellular_component |
| GO:0034235 | GPI anchor binding | TAS | molecular_function |
| GO:0042765 | GPI-anchor transamidase complex | IEA IMP | cellular_component |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9161752897 | 0.0052535884 | 0.9999902473 | 0.1475770544 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2765292945 |
| GSE13712_SHEAR | Down | -0.0906880706 |
| GSE13712_STATIC | Up | 0.0038143303 |
| GSE19018 | Up | 0.3724053352 |
| GSE19899_A1 | Down | -1.2938686089 |
| GSE19899_A2 | Down | -1.0636096916 |
| PubMed_21979375_A1 | Down | -0.9501804866 |
| PubMed_21979375_A2 | Down | -1.7687748635 |
| GSE35957 | Up | 0.0437560289 |
| GSE36640 | Down | -0.2005031455 |
| GSE54402 | Down | -1.0962193874 |
| GSE9593 | Up | 0.1860256000 |
| GSE43922 | Down | -1.3053197727 |
| GSE24585 | Up | 0.2787878562 |
| GSE37065 | Down | -0.0091635140 |
| GSE28863_A1 | Down | -0.0465757364 |
| GSE28863_A2 | Up | 0.7772896519 |
| GSE28863_A3 | Down | -0.8396384211 |
| GSE28863_A4 | Down | -0.3586863524 |
| GSE48662 | Down | -0.0454723994 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
