HCSGD entry for CASP12


1. General information

Official gene symbolCASP12
Entrez ID100506742
Gene full namecaspase 12 (gene/pseudogene)
Other gene symbolsCASP-12 CASP12P1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004197Cysteine-type endopeptidase activityIEAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0030968Endoplasmic reticulum unfolded protein responseIEAbiological_process
GO:0042981Regulation of apoptotic processIEAbiological_process
GO:0070059Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07676102350.88889330570.58579991311.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0036681711
GSE13712_SHEARDown-0.3911366438
GSE13712_STATICDown-0.6823453596
GSE19018Down-0.0723534003
GSE19899_A1Up0.1313310180
GSE19899_A2Up0.4233715906
PubMed_21979375_A1Up0.3122601040
PubMed_21979375_A2Up0.6058401092
GSE35957Up0.1223192787
GSE36640Up1.3135805017
GSE54402Down-0.0400286817
GSE9593Up0.0616882850
GSE43922Up0.8558281739
GSE24585Up0.0274113168
GSE37065Up0.0202183786
GSE28863_A1Down-0.0476015214
GSE28863_A2Up0.1369854041
GSE28863_A3Up0.0860258785
GSE28863_A4Down-0.0776205641
GSE48662Up0.3345424662

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.