HCSGD entry for FARSB
1. General information
| Official gene symbol | FARSB |
|---|---|
| Entrez ID | 10056 |
| Gene full name | phenylalanyl-tRNA synthetase, beta subunit |
| Other gene symbols | FARSLB FRSB PheHB PheRS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004826 | Phenylalanine-tRNA ligase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006432 | Phenylalanyl-tRNA aminoacylation | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8893253372 | 0.0554073174 | 0.9999902473 | 0.4434101551 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2034565998 |
| GSE13712_SHEAR | Up | 0.1298474525 |
| GSE13712_STATIC | Up | 0.1596861226 |
| GSE19018 | Down | -0.5526256591 |
| GSE19899_A1 | Up | 0.0874825206 |
| GSE19899_A2 | Down | -0.2512267180 |
| PubMed_21979375_A1 | Up | 0.3553200771 |
| PubMed_21979375_A2 | Down | -0.1035298124 |
| GSE35957 | Down | -0.4171560201 |
| GSE36640 | Down | -0.3093667909 |
| GSE54402 | Up | 0.2369779542 |
| GSE9593 | Down | -0.1601241140 |
| GSE43922 | Down | -0.0152397143 |
| GSE24585 | Down | -0.5570579024 |
| GSE37065 | Down | -0.4269820421 |
| GSE28863_A1 | Down | -0.3533113753 |
| GSE28863_A2 | Up | 0.3386974273 |
| GSE28863_A3 | Down | -0.6088052576 |
| GSE28863_A4 | Up | 0.0064869999 |
| GSE48662 | Down | -0.3297439361 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Phenylalanine | DB00120 | NUTR00044 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-744-5p | MIMAT0004945 | MIRT037617 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041199 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048577 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
