HCSGD entry for CDH11
1. General information
| Official gene symbol | CDH11 |
|---|---|
| Entrez ID | 1009 |
| Gene full name | cadherin 11, type 2, OB-cadherin (osteoblast) |
| Other gene symbols | CAD11 CDHOB OB OSF-4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001501 | Skeletal system development | TAS | biological_process |
| GO:0001503 | Ossification | NAS | biological_process |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA TAS | cellular_component |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0007156 | Homophilic cell adhesion | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0021957 | Corticospinal tract morphogenesis | IEA | biological_process |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0034332 | Adherens junction organization | TAS | biological_process |
| GO:0045216 | Cell-cell junction organization | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9733015197 | 0.0001486114 | 0.9999902473 | 0.0214923077 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.2497875729 |
| GSE13712_SHEAR | Down | -3.5264794094 |
| GSE13712_STATIC | Down | -2.3625100674 |
| GSE19018 | Down | -1.3095677816 |
| GSE19899_A1 | Down | -1.4936330008 |
| GSE19899_A2 | Down | -0.6585369337 |
| PubMed_21979375_A1 | Down | -0.9601813744 |
| PubMed_21979375_A2 | Down | -1.4384795539 |
| GSE35957 | Up | 0.2991306111 |
| GSE36640 | Down | -0.7901540562 |
| GSE54402 | Down | -1.0127978230 |
| GSE9593 | Down | -0.3596321105 |
| GSE43922 | Down | -0.8753763316 |
| GSE24585 | Up | 0.0089274455 |
| GSE37065 | Down | -0.2964623428 |
| GSE28863_A1 | Up | 0.8713909185 |
| GSE28863_A2 | Up | 0.3938934503 |
| GSE28863_A3 | Down | -0.2886289166 |
| GSE28863_A4 | Down | -0.0999166048 |
| GSE48662 | Down | -0.3114883853 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018564 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022977 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | NA | hsa-miR-204 | 20369013 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 17951672 | Surface markers that can be used to characterize FLS include positive staining for VCAM-1, CD44, CD55, CD90 (Thy-1), and cadherin-11, coupled with the absence of macrophage markers such as CD14 or CD68 |
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