HCSGD entry for ACTR2
1. General information
| Official gene symbol | ACTR2 |
|---|---|
| Entrez ID | 10097 |
| Gene full name | ARP2 actin-related protein 2 homolog (yeast) |
| Other gene symbols | ARP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005885 | Arp2/3 protein complex | IEA RCA TAS | cellular_component |
| GO:0006928 | Cellular component movement | TAS | biological_process |
| GO:0007163 | Establishment or maintenance of cell polarity | IEA | biological_process |
| GO:0008356 | Asymmetric cell division | IEA | biological_process |
| GO:0015629 | Actin cytoskeleton | TAS | cellular_component |
| GO:0016482 | Cytoplasmic transport | IEA | biological_process |
| GO:0030478 | Actin cap | IEA | cellular_component |
| GO:0033206 | Meiotic cytokinesis | IEA | biological_process |
| GO:0034314 | Arp2/3 complex-mediated actin nucleation | IEA | biological_process |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0042995 | Cell projection | IEA | cellular_component |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0051653 | Spindle localization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3927654230 | 0.1389387143 | 0.9999902473 | 0.7173633778 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3628637762 |
| GSE13712_SHEAR | Up | 0.3242824890 |
| GSE13712_STATIC | Up | 0.0455830872 |
| GSE19018 | Up | 0.0055422007 |
| GSE19899_A1 | Up | 0.1657709368 |
| GSE19899_A2 | Down | -0.1665667995 |
| PubMed_21979375_A1 | Down | -0.2218092545 |
| PubMed_21979375_A2 | Down | -0.4266285584 |
| GSE35957 | Up | 0.3536784802 |
| GSE36640 | Down | -0.2617903144 |
| GSE54402 | Up | 0.0308566526 |
| GSE9593 | Up | 0.2464555329 |
| GSE43922 | Up | 0.0051127811 |
| GSE24585 | Down | -0.1889907186 |
| GSE37065 | Down | -0.0944069197 |
| GSE28863_A1 | Up | 0.3273544098 |
| GSE28863_A2 | Up | 0.5085606090 |
| GSE28863_A3 | Down | -0.2355645033 |
| GSE28863_A4 | Down | -0.0449280860 |
| GSE48662 | Down | -0.4189482283 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide | DB08235 | - |
| (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one | DB08236 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020780 | Reporter assay;Other | Non-Functional MTI | 20584899 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021852 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024581 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026515 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028015 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030897 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
