HCSGD entry for TENM1

1. General information

Official gene symbolTENM1
Entrez ID10178
Gene full nameteneurin transmembrane protein 1
Other gene symbolsODZ1 ODZ3 TEN-M1 TNM TNM1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005576Extracellular regionTAScellular_component
GO:0005634NucleusISScellular_component
GO:0005737CytoplasmISScellular_component
GO:0005783Endoplasmic reticulumISScellular_component
GO:0005794Golgi apparatusISScellular_component
GO:0005856CytoskeletonISScellular_component
GO:0005886Plasma membraneISScellular_component
GO:0005887Integral component of plasma membraneISScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006359Regulation of transcription from RNA polymerase III promoterISSbiological_process
GO:0006950Response to stressIEAbiological_process
GO:0006955Immune responseTASbiological_process
GO:0007218Neuropeptide signaling pathwayIEAbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0008201Heparin bindingTASmolecular_function
GO:0008285Negative regulation of cell proliferationTASbiological_process
GO:0016363Nuclear matrixISScellular_component
GO:0016607Nuclear speckISScellular_component
GO:0030838Positive regulation of actin filament polymerizationISSbiological_process
GO:0033138Positive regulation of peptidyl-serine phosphorylationISSbiological_process
GO:0042803Protein homodimerization activityISSmolecular_function
GO:0043406Positive regulation of MAP kinase activityISSbiological_process
GO:0046982Protein heterodimerization activityISSmolecular_function
GO:0048471Perinuclear region of cytoplasmISScellular_component
GO:0051491Positive regulation of filopodium assemblyISSbiological_process
GO:0090316Positive regulation of intracellular protein transportISSbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02398585540.94452645040.36698245211.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1445271641
GSE13712_SHEARDown-0.1057261964
GSE13712_STATICDown-0.0642071939
GSE19018Up0.0475559806
GSE19899_A1Up0.1820184251
GSE19899_A2Up0.8188172222
PubMed_21979375_A1Up1.3762283085
PubMed_21979375_A2Up1.0256162948
GSE35957Up0.1274852120
GSE36640Up2.4732675746
GSE54402Up0.8273043585
GSE9593Up0.0506698635
GSE43922Up0.5188491172
GSE24585Down-0.3935072751
GSE37065Up0.0408493925
GSE28863_A1Down-0.0305883997
GSE28863_A2Down-0.0884343851
GSE28863_A3Up0.1060792181
GSE28863_A4Up0.0674819202
GSE48662Down-0.0731741167

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 4 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

27067789Our results showed that positive staining of Endoglin (38%) was associated with a higher TNM stage and higher incidence of GCPD (both P <
24959282In the Sirt1-positive expression group, Sirt1 expression correlated with a higher Ki67 index and higher TNM classification, particularly for lymph node invasion and metastasis, and with a higher number of pulmonary vein invasion and lymphatic duct invasion
23645774TNM1, 27
20137575In addition, the mRNA levels of CD28 and CD95 in the peripheral blood of the elderly patients was closely associated with the tumor node metastasis (TNM) stages, grade of cell differentiation and lymph node metastasis status, but not related to pathological types
Entries Per Page
Displaying Page of