HCSGD entry for NME6
1. General information
| Official gene symbol | NME6 |
|---|---|
| Entrez ID | 10201 |
| Gene full name | NME/NM23 nucleoside diphosphate kinase 6 |
| Other gene symbols | IPIA-ALPHA NDK 6 NM23-H6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004550 | Nucleoside diphosphate kinase activity | IDA IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0006183 | GTP biosynthetic process | IEA | biological_process |
| GO:0006228 | UTP biosynthetic process | IEA | biological_process |
| GO:0006241 | CTP biosynthetic process | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0030308 | Negative regulation of cell growth | IDA | biological_process |
| GO:0045839 | Negative regulation of mitosis | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7128133050 | 0.2173628700 | 0.9999902473 | 0.8973838770 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1502286685 |
| GSE13712_SHEAR | Up | 0.5698525071 |
| GSE13712_STATIC | Up | 0.3644116030 |
| GSE19018 | Down | -0.1150342948 |
| GSE19899_A1 | Up | 0.0681056466 |
| GSE19899_A2 | Up | 0.0817408220 |
| PubMed_21979375_A1 | Up | 0.3420602525 |
| PubMed_21979375_A2 | Down | -0.2146589715 |
| GSE35957 | Down | -0.6510468871 |
| GSE36640 | Down | -0.1819507016 |
| GSE54402 | Down | -0.1607767931 |
| GSE9593 | Down | -0.0453772061 |
| GSE43922 | Down | -0.0280716488 |
| GSE24585 | Down | -0.2764974252 |
| GSE37065 | Up | 0.0387143434 |
| GSE28863_A1 | Down | -0.1895092871 |
| GSE28863_A2 | Down | -0.2678666170 |
| GSE28863_A3 | Down | -0.3197888588 |
| GSE28863_A4 | Down | -0.1453126146 |
| GSE48662 | Up | 0.1001141837 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027772 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032439 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
