HCSGD entry for KCNMB2

1. General information

Official gene symbolKCNMB2
Entrez ID10242
Gene full namepotassium large conductance calcium-activated channel, subfamily M, beta member 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001508Action potentialIDAbiological_process
GO:0005513Detection of calcium ionIDAbiological_process
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0006813Potassium ion transportIDAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008076Voltage-gated potassium channel complexIDAcellular_component
GO:0008200Ion channel inhibitor activityTASmolecular_function
GO:0015269Calcium-activated potassium channel activityIDA IEAmolecular_function
GO:0015459Potassium channel regulator activityTASmolecular_function
GO:0016020MembraneIEAcellular_component
GO:0019228Neuronal action potentialIDAbiological_process
GO:0019229Regulation of vasoconstrictionTASbiological_process
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0055085Transmembrane transportIDAbiological_process
GO:0071805Potassium ion transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64558230310.88832054250.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0876532755
GSE13712_SHEARUp0.1411040530
GSE13712_STATICDown-0.0269421222
GSE19018Down-0.0690999626
GSE19899_A1Up0.0988592789
GSE19899_A2Up0.0787187820
PubMed_21979375_A1Up0.1484928743
PubMed_21979375_A2Up0.0906156177
GSE35957Up0.0424610406
GSE36640Down-0.0099935612
GSE54402Down-0.0235972108
GSE9593Down-0.0158321717
GSE43922Up0.0116557312
GSE24585Up0.0720626387
GSE37065Down-0.0454262191
GSE28863_A1Down-0.0408928850
GSE28863_A2Up0.3978910559
GSE28863_A3Up0.1618118811
GSE28863_A4Up0.0655032868
GSE48662Down-0.0157648250

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MiconazoleDB01110 APRD01115
(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-PiperidiniumDB03861 EXPT01846

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.