HCSGD entry for RAMP2

1. General information

Official gene symbolRAMP2
Entrez ID10266
Gene full namereceptor (G protein-coupled) activity modifying protein 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIDAbiological_process
GO:0001570VasculogenesisIMPbiological_process
GO:0001666Response to hypoxiaIEAbiological_process
GO:0002040Sprouting angiogenesisIEA ISSbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005764LysosomeTAScellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0005905Coated pitTAScellular_component
GO:0006171CAMP biosynthetic processIDAbiological_process
GO:0006816Calcium ion transportIDAbiological_process
GO:0006886Intracellular protein transportIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007507Heart developmentIEA ISSbiological_process
GO:0007565Female pregnancyIEAbiological_process
GO:0008217Regulation of blood pressureIEA ISSbiological_process
GO:0008277Regulation of G-protein coupled receptor protein signaling pathwayIEAbiological_process
GO:0008565Protein transporter activityIDA IEAmolecular_function
GO:0009986Cell surfaceIDAcellular_component
GO:0010628Positive regulation of gene expressionIDAbiological_process
GO:0015026Coreceptor activityIEA ISSmolecular_function
GO:0015031Protein transportIDAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030819Positive regulation of cAMP biosynthetic processIDAbiological_process
GO:0031623Receptor internalizationIDA IEAbiological_process
GO:0032355Response to estradiolIEAbiological_process
GO:0032570Response to progesteroneIEAbiological_process
GO:0032870Cellular response to hormone stimulusIEAbiological_process
GO:0034333Adherens junction assemblyIDAbiological_process
GO:0035924Cellular response to vascular endothelial growth factor stimulusIEA ISSbiological_process
GO:0043116Negative regulation of vascular permeabilityIDAbiological_process
GO:0043235Receptor complexIDAcellular_component
GO:0045766Positive regulation of angiogenesisIEA ISSbiological_process
GO:0070830Tight junction assemblyIDAbiological_process
GO:0070831Basement membrane assemblyIEA ISSbiological_process
GO:0072659Protein localization to plasma membraneIDAbiological_process
GO:0097084Vascular smooth muscle cell developmentIEA ISSbiological_process
GO:2000352Negative regulation of endothelial cell apoptotic processIDAbiological_process
GO:2001214Positive regulation of vasculogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93062899970.03860104480.99999024730.3700176985

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0332210826
GSE13712_SHEARDown-2.8694577105
GSE13712_STATICDown-2.5757016736
GSE19018Down-0.0447620490
GSE19899_A1Up0.0638463961
GSE19899_A2Up0.1722018123
PubMed_21979375_A1Up0.0500986863
PubMed_21979375_A2Down-0.1206885002
GSE35957Up0.2044162745
GSE36640Down-0.5098000795
GSE54402Down-0.4470725242
GSE9593Up0.0156190954
GSE43922Up0.0212561550
GSE24585Down-0.0469663664
GSE37065Up0.1173580118
GSE28863_A1Down-0.1731130850
GSE28863_A2Down-0.2017443362
GSE28863_A3Up0.1971060154
GSE28863_A4Up0.0195397203
GSE48662Up0.0551548524

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

PramlintideDB01278 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.