HCSGD entry for NET1


1. General information

Official gene symbolNET1
Entrez ID10276
Gene full nameneuroepithelial cell transforming 1
Other gene symbolsARHGEF8 NET1A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001558Regulation of cell growthNASbiological_process
GO:0005085Guanyl-nucleotide exchange factor activityTASmolecular_function
GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0032321Positive regulation of Rho GTPase activityIMPbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0043065Positive regulation of apoptotic processIDA TASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0070301Cellular response to hydrogen peroxideIDAbiological_process
GO:0071479Cellular response to ionizing radiationIDAbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93001055430.00250348770.99999024730.0986441617

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2154649044
GSE13712_SHEARDown-0.6353821651
GSE13712_STATICDown-0.1281701679
GSE19018Down-0.6126101406
GSE19899_A1Down-0.4987426819
GSE19899_A2Down-1.0206498726
PubMed_21979375_A1Down-1.7077805813
PubMed_21979375_A2Down-1.3753294408
GSE35957Down-1.1491393871
GSE36640Down-0.7872840302
GSE54402Up0.4006339936
GSE9593Down-0.2102348972
GSE43922Down-0.5210867704
GSE24585Up0.3247929620
GSE37065Up0.1489513723
GSE28863_A1Down-0.7786017540
GSE28863_A2Up0.4078295751
GSE28863_A3Down-0.8391066069
GSE28863_A4Up0.1664776847
GSE48662Down-0.4270390997

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-340-5pMIMAT0004692MIRT019642SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT029990MicroarrayFunctional MTI (Weak)19088304
hsa-miR-24-3pMIMAT0000080MIRT030610MicroarrayFunctional MTI (Weak)19748357
hsa-miR-320aMIMAT0000510MIRT044778CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.