HCSGD entry for CCL26


1. General information

Official gene symbolCCL26
Entrez ID10344
Gene full namechemokine (C-C motif) ligand 26
Other gene symbolsIMAC MIP-4a MIP-4alpha SCYA26 TSC-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001938Positive regulation of endothelial cell proliferationIDAbiological_process
GO:0005615Extracellular spaceIEAcellular_component
GO:0006935ChemotaxisTASbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0006955Immune responseIEAbiological_process
GO:0007165Signal transductionNASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0008009Chemokine activityIEAmolecular_function
GO:0030335Positive regulation of cell migrationIDAbiological_process
GO:0030838Positive regulation of actin filament polymerizationIDAbiological_process
GO:0032855Positive regulation of Rac GTPase activityIDAbiological_process
GO:0060326Cell chemotaxisTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00955452680.88207347750.24950545631.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.5120657506
GSE13712_SHEARUp0.2154075429
GSE13712_STATICUp0.1804178620
GSE19018Up0.0381444916
GSE19899_A1Up0.0631621704
GSE19899_A2Up0.9554235054
PubMed_21979375_A1Up1.1710336120
PubMed_21979375_A2Up0.9100012011
GSE35957Down-1.0014026043
GSE36640Up0.7610699762
GSE54402Up0.0571046153
GSE9593Up0.6534506807
GSE43922Up0.9003606787
GSE24585Up0.3096758891
GSE37065Up0.0078842703
GSE28863_A1Down-0.3312181647
GSE28863_A2Up0.1460768137
GSE28863_A3Down-0.4690454778
GSE28863_A4Down-0.0209935131
GSE48662Down-0.0850417354

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-25-3pMIMAT0000081MIRT006454Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI22431589
hsa-miR-335-5pMIMAT0000765MIRT017426MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.