HCSGD entry for WARS2


1. General information

Official gene symbolWARS2
Entrez ID10352
Gene full nametryptophanyl tRNA synthetase 2, mitochondrial
Other gene symbolsTrpRS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001570VasculogenesisIEAbiological_process
GO:0004830Tryptophan-tRNA ligase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionIEAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0006418TRNA aminoacylation for protein translationTASbiological_process
GO:0006436Tryptophanyl-tRNA aminoacylationIEAbiological_process
GO:0010467Gene expressionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89753553440.20521112040.99999024730.8786988612

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0551869106
GSE13712_SHEARDown-0.5309739626
GSE13712_STATICDown-0.4220262470
GSE19018Up0.0381423472
GSE19899_A1Up0.0350778666
GSE19899_A2Up0.3637833923
PubMed_21979375_A1Up0.4011236025
PubMed_21979375_A2Up0.2098855313
GSE35957Up0.1293413067
GSE36640Down-0.2720610226
GSE54402Up0.1180603596
GSE9593Down-0.0389567151
GSE43922Down-0.2843749521
GSE24585Down-0.4797928089
GSE37065Down-0.2074811220
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0231999893

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027840MicroarrayFunctional MTI (Weak)19088304
hsa-let-7b-5pMIMAT0000063MIRT032492ProteomicsFunctional MTI (Weak)18668040
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.