HCSGD entry for MYL12B
1. General information
| Official gene symbol | MYL12B |
|---|---|
| Entrez ID | 103910 |
| Gene full name | myosin, light chain 12B, regulatory |
| Other gene symbols | MLC-B MRLC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001725 | Stress fiber | IEA | cellular_component |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006936 | Muscle contraction | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0008360 | Regulation of cell shape | IEA | biological_process |
| GO:0016460 | Myosin II complex | IEA | cellular_component |
| GO:0030018 | Z disc | IEA | cellular_component |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3868340071 | 0.8917968314 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0917968405 |
| GSE13712_SHEAR | Up | 0.3900094772 |
| GSE13712_STATIC | Up | 0.1428878128 |
| GSE19018 | Up | 0.4876163087 |
| GSE19899_A1 | Up | 0.1121898444 |
| GSE19899_A2 | Up | 0.1814185185 |
| PubMed_21979375_A1 | Up | 0.0371498409 |
| PubMed_21979375_A2 | Down | -0.0445247842 |
| GSE35957 | Up | 0.1450366070 |
| GSE36640 | Up | 0.4057233969 |
| GSE54402 | Down | -0.1486566420 |
| GSE9593 | Up | 0.1055181633 |
| GSE43922 | Down | -0.0319353552 |
| GSE24585 | Down | -0.0618824848 |
| GSE37065 | Down | -0.0775748069 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.2386084502 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041406 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
