HCSGD entry for TAB1

1. General information

Official gene symbolTAB1
Entrez ID10454
Gene full nameTGF-beta activated kinase 1/MAP3K7 binding protein 1
Other gene symbols3'-Tab1 MAP3K7IP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000185Activation of MAPKKK activityIEAbiological_process
GO:0000187Activation of MAPK activityTASbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0002224Toll-like receptor signaling pathwayTASbiological_process
GO:0002755MyD88-dependent toll-like receptor signaling pathwayTASbiological_process
GO:0002756MyD88-independent toll-like receptor signaling pathwayTASbiological_process
GO:0003007Heart morphogenesisIEAbiological_process
GO:0003824Catalytic activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0007179Transforming growth factor beta receptor signaling pathwayIEAbiological_process
GO:0007249I-kappaB kinase/NF-kappaB signalingTASbiological_process
GO:0007254JNK cascadeTASbiological_process
GO:0008047Enzyme activator activityTASmolecular_function
GO:0010008Endosome membraneTAScellular_component
GO:0019209Kinase activator activityIEAmolecular_function
GO:0030324Lung developmentIEAbiological_process
GO:0032403Protein complex bindingIEAmolecular_function
GO:0034134Toll-like receptor 2 signaling pathwayTASbiological_process
GO:0034138Toll-like receptor 3 signaling pathwayTASbiological_process
GO:0034142Toll-like receptor 4 signaling pathwayTASbiological_process
GO:0034146Toll-like receptor 5 signaling pathwayTASbiological_process
GO:0034162Toll-like receptor 9 signaling pathwayTASbiological_process
GO:0034166Toll-like receptor 10 signaling pathwayTASbiological_process
GO:0035666TRIF-dependent toll-like receptor signaling pathwayTASbiological_process
GO:0035872Nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayTASbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0038123Toll-like receptor TLR1:TLR2 signaling pathwayTASbiological_process
GO:0038124Toll-like receptor TLR6:TLR2 signaling pathwayTASbiological_process
GO:0043234Protein complexIEAcellular_component
GO:0045087Innate immune responseTASbiological_process
GO:0048273Mitogen-activated protein kinase p38 bindingIEAmolecular_function
GO:0051092Positive regulation of NF-kappaB transcription factor activityTASbiological_process
GO:0051403Stress-activated MAPK cascadeTASbiological_process
GO:0070423Nucleotide-binding oligomerization domain containing signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.29911928120.82760764410.99822280681.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0424771582
GSE13712_SHEARDown-0.4172306933
GSE13712_STATICDown-0.2742885725
GSE19018Down-0.0528616568
GSE19899_A1Up0.0424650178
GSE19899_A2Up0.1533545755
PubMed_21979375_A1Up0.2538153329
PubMed_21979375_A2Up0.7845786175
GSE35957Down-0.1573964555
GSE36640Down-0.1838227625
GSE54402Up0.1202058879
GSE9593Down-0.1633638717
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.3973818500
GSE28863_A2Up0.2570663988
GSE28863_A3Up0.3211570427
GSE28863_A4Up0.0466766642
GSE48662Up0.0599160446

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30d-5pMIMAT0000245MIRT047792CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.