HCSGD entry for RPP38
1. General information
| Official gene symbol | RPP38 |
|---|---|
| Entrez ID | 10557 |
| Gene full name | ribonuclease P/MRP 38kDa subunit |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004526 | Ribonuclease P activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005655 | Nucleolar ribonuclease P complex | TAS | cellular_component |
| GO:0008033 | TRNA processing | IEA | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | TAS | biological_process |
| GO:0090501 | RNA phosphodiester bond hydrolysis | TAS | biological_process |
| GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0390256031 | 0.5655579309 | 0.4453448635 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5074293256 |
| GSE13712_SHEAR | Down | -0.1702879227 |
| GSE13712_STATIC | Down | -0.1592032854 |
| GSE19018 | Down | -0.1921628968 |
| GSE19899_A1 | Up | 0.3241050899 |
| GSE19899_A2 | Up | 1.2394157195 |
| PubMed_21979375_A1 | Up | 1.9872214162 |
| PubMed_21979375_A2 | Up | 1.1037479809 |
| GSE35957 | Down | -0.7268101123 |
| GSE36640 | Down | -0.5672944968 |
| GSE54402 | Up | 0.3531666800 |
| GSE9593 | Up | 0.1903824196 |
| GSE43922 | Up | 0.3135717406 |
| GSE24585 | Down | -0.2612047421 |
| GSE37065 | Up | 0.1657185129 |
| GSE28863_A1 | Up | 0.0618008239 |
| GSE28863_A2 | Down | -0.0260063486 |
| GSE28863_A3 | Down | -0.1770134717 |
| GSE28863_A4 | Up | 0.0239768886 |
| GSE48662 | Down | -0.2430864371 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT001597 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
