HCSGD entry for CCT2
1. General information
| Official gene symbol | CCT2 |
|---|---|
| Entrez ID | 10576 |
| Gene full name | chaperonin containing TCP1, subunit 2 (beta) |
| Other gene symbols | 99D8.1 CCT-beta CCTB PRO1633 TCP-1-beta |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002199 | Zona pellucida receptor complex | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | NAS TAS | cellular_component |
| GO:0005832 | Chaperonin-containing T-complex | IEA | cellular_component |
| GO:0005874 | Microtubule | IDA | cellular_component |
| GO:0006457 | Protein folding | IEA NAS TAS | biological_process |
| GO:0007339 | Binding of sperm to zona pellucida | IEA | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0044297 | Cell body | IEA | cellular_component |
| GO:0051082 | Unfolded protein binding | IEA NAS | molecular_function |
| GO:0051084 | 'de novo' posttranslational protein folding | TAS | biological_process |
| GO:0051131 | Chaperone-mediated protein complex assembly | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4858905285 | 0.0791585274 | 0.9999902473 | 0.5318273980 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2789344526 |
| GSE13712_SHEAR | Down | -0.0096041096 |
| GSE13712_STATIC | Up | 0.0872870689 |
| GSE19018 | Down | -1.0642916710 |
| GSE19899_A1 | Up | 0.1503904566 |
| GSE19899_A2 | Down | -0.1309711977 |
| PubMed_21979375_A1 | Up | 0.3107475517 |
| PubMed_21979375_A2 | Down | -0.3673965800 |
| GSE35957 | Down | -0.3007080824 |
| GSE36640 | Down | -0.5846184454 |
| GSE54402 | Up | 0.4481292606 |
| GSE9593 | Down | -0.3703188808 |
| GSE43922 | Up | 0.2051787596 |
| GSE24585 | Down | -0.2337900029 |
| GSE37065 | Down | -0.1532941834 |
| GSE28863_A1 | Down | -0.1281648718 |
| GSE28863_A2 | Up | 0.1735965002 |
| GSE28863_A3 | Down | -0.6210763077 |
| GSE28863_A4 | Up | 0.3518900423 |
| GSE48662 | Down | -0.5831487980 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT021019 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041339 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
