HCSGD entry for GNLY
1. General information
| Official gene symbol | GNLY |
|---|---|
| Entrez ID | 10578 |
| Gene full name | granulysin |
| Other gene symbols | 519 D2S69E LAG-2 LAG2 NKG5 TLA519 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0006968 | Cellular defense response | TAS | biological_process |
| GO:0031640 | Killing of cells of other organism | IEA | biological_process |
| GO:0042742 | Defense response to bacterium | IEA | biological_process |
| GO:0050832 | Defense response to fungus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6580680673 | 0.8615723301 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0290715306 |
| GSE13712_SHEAR | Up | 0.0711168926 |
| GSE13712_STATIC | Down | -0.0364185725 |
| GSE19018 | Up | 0.1289620353 |
| GSE19899_A1 | Up | 0.0497079381 |
| GSE19899_A2 | Up | 0.0218714523 |
| PubMed_21979375_A1 | Up | 0.0105598935 |
| PubMed_21979375_A2 | Up | 0.0696006543 |
| GSE35957 | Up | 0.1150183753 |
| GSE36640 | Up | 0.1700244917 |
| GSE54402 | Down | -0.1860553739 |
| GSE9593 | Up | 0.1219797583 |
| GSE43922 | Down | -0.0306646124 |
| GSE24585 | Down | -0.0347625049 |
| GSE37065 | Down | -0.0041891240 |
| GSE28863_A1 | Down | -0.0881984424 |
| GSE28863_A2 | Down | -0.1230794328 |
| GSE28863_A3 | Up | 0.2650010503 |
| GSE28863_A4 | Up | 0.1432585719 |
| GSE48662 | Up | 0.0079501953 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 3[N-Morpholino]Propane Sulfonic Acid | DB03434 | EXPT02224 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 20545466 | 519, p = 0 |
| 19190150 | Significant stress-related differences in telomere length were seen in women ages 55 years and older (-289bp; 95% CI, -519 to -59), those with recent major losses (-420bp; 95% CI, -814 to -27), and those with above-average urinary catecholamines (e |
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