HCSGD entry for ERLIN1
1. General information
| Official gene symbol | ERLIN1 |
|---|---|
| Entrez ID | 10613 |
| Gene full name | ER lipid raft associated 1 |
| Other gene symbols | C10orf69 Erlin-1 KE04 KEO4 SPFH1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0043234 | Protein complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9923275901 | 0.0076934045 | 0.9999902473 | 0.1753230303 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1564918827 |
| GSE13712_SHEAR | Down | -0.1013038916 |
| GSE13712_STATIC | Down | -0.0888651892 |
| GSE19018 | Down | -0.0606761270 |
| GSE19899_A1 | Down | -0.8225466168 |
| GSE19899_A2 | Down | -1.0340395976 |
| PubMed_21979375_A1 | Down | -0.6261276430 |
| PubMed_21979375_A2 | Down | -1.4095999882 |
| GSE35957 | Down | -0.3222706906 |
| GSE36640 | Down | -0.8832602328 |
| GSE54402 | Down | -0.4909290366 |
| GSE9593 | Up | 0.4390532211 |
| GSE43922 | Down | -0.2349836515 |
| GSE24585 | Down | -0.1987050283 |
| GSE37065 | Down | -0.0323779214 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.2712352998 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025383 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025383 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028682 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039885 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047443 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047667 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047975 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT051010 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
