HCSGD entry for IGF2BP3
1. General information
| Official gene symbol | IGF2BP3 |
|---|---|
| Entrez ID | 10643 |
| Gene full name | insulin-like growth factor 2 mRNA binding protein 3 |
| Other gene symbols | CT98 IMP-3 IMP3 KOC1 VICKZ3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | TAS | molecular_function |
| GO:0003730 | MRNA 3'-UTR binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0017148 | Negative regulation of translation | ISS | biological_process |
| GO:0042035 | Regulation of cytokine biosynthetic process | IC | biological_process |
| GO:0045182 | Translation regulator activity | ISS | molecular_function |
| GO:0048027 | MRNA 5'-UTR binding | IDA | molecular_function |
| GO:0051028 | MRNA transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0445469815 | 0.5653113028 | 0.4696202638 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.7200522328 |
| GSE13712_SHEAR | Up | 0.9950610971 |
| GSE13712_STATIC | Up | 0.9057836084 |
| GSE19018 | Up | 0.0223140076 |
| GSE19899_A1 | Up | 0.0239660315 |
| GSE19899_A2 | Down | -0.1167969125 |
| PubMed_21979375_A1 | Down | -0.8729088663 |
| PubMed_21979375_A2 | Down | -0.4839897607 |
| GSE35957 | Up | 0.4921767095 |
| GSE36640 | Up | 0.1338876739 |
| GSE54402 | Up | 0.5387589309 |
| GSE9593 | Up | 0.3556523151 |
| GSE43922 | Down | -0.2131194227 |
| GSE24585 | Up | 0.0950519044 |
| GSE37065 | Up | 0.1395389547 |
| GSE28863_A1 | Down | -0.0435069067 |
| GSE28863_A2 | Up | 0.2036483156 |
| GSE28863_A3 | Down | -0.0191574165 |
| GSE28863_A4 | Down | -0.0230069589 |
| GSE48662 | Down | -0.2744136205 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025416 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT026059 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032130 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032297 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-320a | MIMAT0000510 | MIRT044404 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045123 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051466 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
