HCSGD entry for CLDN16

1. General information

Official gene symbolCLDN16
Entrez ID10686
Gene full nameclaudin 16
Other gene symbolsHOMG3 PCLN1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005198Structural molecule activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0005923Tight junctionIEA ISScellular_component
GO:0006812Cation transportTASbiological_process
GO:0006875Cellular metal ion homeostasisTASbiological_process
GO:0007588ExcretionTASbiological_process
GO:0015095Magnesium ion transmembrane transporter activityTASmolecular_function
GO:0015693Magnesium ion transportTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016338Calcium-independent cell-cell adhesionISSbiological_process
GO:0030001Metal ion transportTASbiological_process
GO:0034220Ion transmembrane transportTASbiological_process
GO:0042802Identical protein bindingISSmolecular_function
GO:0055085Transmembrane transportTASbiological_process
GO:0072511Divalent inorganic cation transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.16516952240.91717381180.80349746811.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0854548019
GSE13712_SHEARUp0.1558874005
GSE13712_STATICDown-0.0084631701
GSE19018Up0.1118714157
GSE19899_A1Up0.1075821771
GSE19899_A2Up0.0251773866
PubMed_21979375_A1Up0.4817781185
PubMed_21979375_A2Down-0.1622381653
GSE35957Up0.1764137390
GSE36640Up0.4475337342
GSE54402Up0.0120799045
GSE9593Down-0.3774986378
GSE43922Up0.8858975892
GSE24585Up0.1339968502
GSE37065Up0.1650283964
GSE28863_A1Down-0.0166055170
GSE28863_A2Down-0.0625411669
GSE28863_A3Up0.1407146012
GSE28863_A4Up0.1002445483
GSE48662Up0.1582655976

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.