HCSGD entry for KIF1C
1. General information
| Official gene symbol | KIF1C |
|---|---|
| Entrez ID | 10749 |
| Gene full name | kinesin family member 1C |
| Other gene symbols | LTXS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003774 | Motor activity | TAS | molecular_function |
| GO:0003777 | Microtubule motor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005871 | Kinesin complex | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0006890 | Retrograde vesicle-mediated transport, Golgi to ER | IEA | biological_process |
| GO:0007018 | Microtubule-based movement | IEA | biological_process |
| GO:0008017 | Microtubule binding | IEA | molecular_function |
| GO:0008152 | Metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1823455112 | 0.2370773033 | 0.8361526481 | 0.9368130461 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3577605501 |
| GSE13712_SHEAR | Up | 0.0278388950 |
| GSE13712_STATIC | Down | -0.0350667342 |
| GSE19018 | Up | 0.1683780831 |
| GSE19899_A1 | Down | -0.2597842963 |
| GSE19899_A2 | Down | -0.1072035839 |
| PubMed_21979375_A1 | Down | -0.9486459353 |
| PubMed_21979375_A2 | Up | 0.0269851064 |
| GSE35957 | Up | 0.7117807394 |
| GSE36640 | Up | 1.5630609705 |
| GSE54402 | Up | 0.0835284484 |
| GSE9593 | Up | 0.5729322365 |
| GSE43922 | Down | -0.2011483821 |
| GSE24585 | Down | -0.8965054442 |
| GSE37065 | Down | -0.2233329142 |
| GSE28863_A1 | Down | -0.1263870541 |
| GSE28863_A2 | Down | -0.2384610432 |
| GSE28863_A3 | Up | 0.0609225520 |
| GSE28863_A4 | Up | 0.0879346399 |
| GSE48662 | Up | 0.3039060701 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029029 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036900 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-3p | MIMAT0003887 | MIRT039061 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041907 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045685 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051959 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052743 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
