HCSGD entry for CPLX2


1. General information

Official gene symbolCPLX2
Entrez ID10814
Gene full namecomplexin 2
Other gene symbols921-L CPX-2 CPX2 Hfb1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005829CytosolIEAcellular_component
GO:0006836Neurotransmitter transportIEAbiological_process
GO:0006904Vesicle docking involved in exocytosisTASbiological_process
GO:0007399Nervous system developmentIEAbiological_process
GO:0016079Synaptic vesicle exocytosisIEAbiological_process
GO:0017075Syntaxin-1 bindingIEAmolecular_function
GO:0019905Syntaxin bindingIEAmolecular_function
GO:0030154Cell differentiationIEAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0031915Positive regulation of synaptic plasticityIEA ISSbiological_process
GO:0042629Mast cell granuleIEAcellular_component
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043303Mast cell degranulationIEAbiological_process
GO:0045202SynapseIEAcellular_component
GO:0048306Calcium-dependent protein bindingIEAmolecular_function
GO:0070033Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71545499790.89040684620.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0718001686
GSE13712_SHEARDown-0.0441520557
GSE13712_STATICDown-0.0638157388
GSE19018Up0.1161811183
GSE19899_A1Up0.0544656618
GSE19899_A2Up0.1506116989
PubMed_21979375_A1Up0.1837006751
PubMed_21979375_A2Down-0.0779770037
GSE35957Up0.1534960195
GSE36640Up0.0076578919
GSE54402Down-0.0016348757
GSE9593Up0.1244832659
GSE43922Up0.0253425796
GSE24585Down-0.1146196379
GSE37065Down-0.0502722247
GSE28863_A1Down-0.0814597211
GSE28863_A2Up0.1653192746
GSE28863_A3Up0.1652602185
GSE28863_A4Up0.0571530168
GSE48662Up0.1108608089

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.