HCSGD entry for COPS6
1. General information
| Official gene symbol | COPS6 |
|---|---|
| Entrez ID | 10980 |
| Gene full name | COP9 signalosome subunit 6 |
| Other gene symbols | CSN6 MOV34-34KD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0008180 | COP9 signalosome | IDA IEA | cellular_component |
| GO:0010388 | Cullin deneddylation | IDA | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9560994377 | 0.0536642453 | 0.9999902473 | 0.4366976529 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1009952891 |
| GSE13712_SHEAR | Up | 0.2623679855 |
| GSE13712_STATIC | Up | 0.0834477423 |
| GSE19018 | Down | -0.0668040567 |
| GSE19899_A1 | Down | -0.4942563773 |
| GSE19899_A2 | Down | -0.0270287658 |
| PubMed_21979375_A1 | Down | -0.6132661003 |
| PubMed_21979375_A2 | Down | -0.2643497842 |
| GSE35957 | Down | -0.3056030936 |
| GSE36640 | Down | -0.1692309674 |
| GSE54402 | Up | 0.1001194173 |
| GSE9593 | Down | -0.0849640076 |
| GSE43922 | Down | -0.1338183446 |
| GSE24585 | Up | 0.0951983620 |
| GSE37065 | Down | -0.1901567952 |
| GSE28863_A1 | Down | -0.5120435187 |
| GSE28863_A2 | Down | -0.0085303143 |
| GSE28863_A3 | Down | -0.3960977766 |
| GSE28863_A4 | Down | -0.0710018266 |
| GSE48662 | Down | -0.4519696892 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7i-5p | MIMAT0000415 | MIRT024115 | Western blot | Functional MTI | 21530537 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT032093 | Western blot | Functional MTI | 21530537 |
| hsa-let-7e-3p | MIMAT0004485 | MIRT032097 | Western blot | Functional MTI | 21530537 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT032192 | Western blot | Functional MTI | 21530537 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043782 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049676 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
